Symbol
Name
ID

Nod2
nucleotide-binding oligomerization domain containing 2
MGI:2429397

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Human Phenotypes

Epistaxis

Abnormal bone marrow cell morphology

Hemolytic anemia

Neutrophilia

Leukocytosis

Leukopenia

Hemophagocytosis

Superficial thrombophlebitis

Hyperfibrinogenemia

Thrombocytopenia

Elevated erythrocyte sedimentation rate

Abnormality of the spleen

Splenomegaly

Hepatosplenomegaly

Disease(s) Associated with NOD2

Behcet's disease

familial mediterranean fever

graft-versus-host disease

leprosy

systemic lupus erythematosus

Mouse Phenotypes		impaired macrophage phagocytosis	impaired neutrophil phagocytosis	increased double-negative T cell number	increased neutrophil cell number	increased CD4-positive, alpha-beta T cell number	increased leukocyte cell number	abnormal macrophage morphology	decreased IgG level	abnormal T-helper 1 physiology	abnormal macrophage physiology
Availability	Mouse Genotype	impaired macrophage phagocytosis	impaired neutrophil phagocytosis	increased double-negative T cell number	increased neutrophil cell number	increased CD4-positive, alpha-beta T cell number	increased leukocyte cell number	abnormal macrophage morphology	decreased IgG level	abnormal T-helper 1 physiology	abnormal macrophage physiology
	Nod2^tm1Daph/Nod2^tm1Daph
	Nod2^tm1Flv/Nod2^tm1Flv
	Nod2^tm1Jhgt/Nod2^tm1Jhgt
	Nod2^tm1Mka/Nod2^tm1Mka
	Nod2^tm1Pmu/Nod2^tm1Pmu

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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